© EMBL Photolab 2019 Eppendorf Young Investigator Award 2019Eppendorf Young Investigator Award 2019:
Austrian Georg E. Winter

Heidelberg 27-06-2019. The Hamburg life science company awarded its highly prestigious research prize at the European Molecular Biology Laboratory (EMBL) at Heidelberg for the twenty-fourth time. The winner is Georg Winter, Principal Investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna (AT).

The jury, which reaches its decision independent of the industry sponsor, honoured Dr. Winter for his pioneering work developing a method for targeting specific proteins for degradation using heterobifunctional chemical compounds to specifically recruit ubiquitin E3 ligases to the intended protein target for destruction. The research already resulted in several patents, which Jury Chairman Prof. Reinhard Jahn praised during the ceremony June 27. “This powerful system enables targeting of previously undruggable targets and shows promise both in cells and in vivo in model systems as an emerging therapy.”

Photo above (left to right): Drs. Axel Jahns and Wilhelm Plüster, Eppendorf AG; Prof. Laura Machesky, Beatson Institute for Cancer Research; Dr. Georg Winter, OeAW-CeMM; Profs. Maria Leptin, European Molecular Biology Laboratory and Reinhard Jahn, Max-Planck-Institut für biophysikalische Chemie.

Sources: Eppendorf AG / EMBL

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Editor's Note

Georg E. Winter (1985) studied molecular biotechnology at FH Campus Wien (Verein zur Förderung des Fachhochschul-, Entwicklungs- und Forschungszentrums im Süden Wiens) obtaining a Master being trained in Thomas Jenuwein’s lab at the Institute of Molecular Pathology (IMP, Boehringer Ingelheim), Vienna Biocenter. In 2008 he moved to CeMM, Center for Molecular Medicine of the Österreichische Akademie der Wissenschaften to pursue doctoral studies under the supervision of Giulio Superti-Furga. After obtaining his PhD in 2013 he moved as post-doctoral researcher to James Bradner’s Laboratory at the Department of Medical Oncology, Dana-Farber Cancer Institute, Boston (US) supported by a Longterm Fellowship by EMBO. This work resulted in refined drug development techniques and several patents of pharmacological inhibitors of multidomain scaffold proteins. Patents are owned by Dana-Farber. Since 2016 he runs his own group at CeMM focusing on chemical genetics and proteomics. In the last years he won several accolades, of which the Eppendorf Award is the most recent prestigious prize endowed with €20,000 ($22,560; £17,900).

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